In terms of overall gaming performance, the graphical capabilities of the AMD Radeon RX 5300M are massively better than the AMD Radeon R9 M365X 4GB.

The Radeon RX 5300M has a 375 MHz higher core clock speed and 48 more Texture Mapping Units than the R9 M365X. This results in the Radeon RX 5300M providing 63 GTexel/s better texturing performance. This still holds weight but shader performance is generally more relevant, particularly since both of these GPUs support at least DirectX 10.

The Radeon RX 5300M has a 375 MHz higher core clock speed and 16 more Render Output Units than the R9 M365X. This results in the Radeon RX 5300M providing 22 GPixel/s better pixeling performance. However, both GPUs support DirectX 9 or above, and pixeling performance is only really relevant when comparing older cards.

The Radeon RX 5300M was released over three years more recently than the R9 M365X, and so the Radeon RX 5300M is likely to have far better driver support, meaning it will be much more optimized and ultimately superior to the R9 M365X when running the latest games.

The R9 M365X has 1024 MB more video memory than the Radeon RX 5300M, so is likely to be much better at displaying game textures at higher resolutions. However, overall, the Radeon RX 5300M has superior memory performance.

The Radeon RX 5300M has 160 GB/sec greater memory bandwidth than the R9 M365X, which means that the memory performance of the Radeon RX 5300M is massively better than the R9 M365X.

The Radeon RX 5300M has 1408 Shader Processing Units and the Radeon R9 M365X 4GB has 640. However, the actual shader performance of the Radeon RX 5300M is 1322 and the actual shader performance of the R9 M365X is 340. The Radeon RX 5300M having 982 better shader performance and an altogether better performance when taking into account other relevant data means that the Radeon RX 5300M delivers a massively smoother and more efficient experience when processing graphical data than the R9 M365X.

The Radeon RX 5300M transistor size technology is 21 nm (nanometers) smaller than the R9 M365X. This means that the Radeon RX 5300M is expected to run slightly cooler and achieve higher clock frequencies than the R9 M365X.

The Radeon RX 5300M requires 85 Watts to run and the Radeon R9 M365X 4GB requires 50 Watts. We would recommend a PSU with at least 450 Watts for the Radeon RX 5300M. The Radeon RX 5300M requires 35 Watts more than the R9 M365X to run. The difference is significant enough that the Radeon RX 5300M may have a slight adverse affect on your yearly electricity bills in comparison to the R9 M365X.