In terms of overall gaming performance, the graphical capabilities of the AMD Radeon R9 M270X are marginally better than the AMD Radeon R9 M365X 4GB.

The Radeon R9 M270X has a 100 MHz higher core clock speed and 8 more Texture Mapping Units than the R9 M365X. This results in the Radeon R9 M270X providing 9.8 GTexel/s better texturing performance. This still holds weight but shader performance is generally more relevant, particularly since both of these GPUs support at least DirectX 10.

The Radeon R9 M270X has a 100 MHz higher core clock speed than the R9 M365X and the same number of Render Output Units. This results in the Radeon R9 M270X providing 1.6 GPixel/s better pixeling performance. However, both GPUs support DirectX 9 or above, and pixeling performance is only really relevant when comparing older cards.

The R9 M365X was released over a year more recently than the Radeon R9 M270X, and so the R9 M365X is likely to have better driver support, meaning it will be more optimized for running the latest games when compared to the Radeon R9 M270X.

The R9 M365X has 2048 MB more video memory than the Radeon R9 M270X, so is likely to be much better at displaying game textures at higher resolutions. This is supported by the fact that the R9 M365X also has superior memory performance overall.

The memory bandwidth of the Radeon R9 M365X 4GB and the Radeon R9 M270X are the same, which means the R9 M365X and the Radeon R9 M270X have equal limitations when it comes to graphical data transfer.

Both the Radeon R9 M365X 4GB and the Radeon R9 M270X have 640 Shader Processing Units. While the two GPUs have the same number of SPUs, the actual performance delivered by the Radeon R9 M270X is 496 and by the R9 M365X is 496. Knowing that the shader performance of the Radeon R9 M270X is superior, it is not necessary to examine the GPUs' respective Texture and Pixel Fill Rates.

The Radeon R9 M365X 4GB requires 50 Watts to run and the Radeon R9 M270X requires 50 Watts. The two GPUs require the same amount of wattage to run. As such, there is no need to worry about which will more significantly affect your yearly electricity bills.