In terms of overall gaming performance, the graphical capabilities of the AMD Radeon HD 8850M are massively better than the Nvidia NVS 2100M.

The Radeon HD 8850M was released over three years more recently than the NVS 2100M, and so the Radeon HD 8850M is likely to have far better driver support, meaning it will be much more optimized and ultimately superior to the NVS 2100M when running the latest games.

The Radeon HD 8850M has 1536 MB more video memory than the NVS 2100M, so is likely to be much better at displaying game textures at higher resolutions. This is supported by the fact that the Radeon HD 8850M also has superior memory performance overall.

The Radeon HD 8850M has 19.2 GB/sec greater memory bandwidth than the NVS 2100M, which means that the memory performance of the Radeon HD 8850M is slightly better than the NVS 2100M.

The Radeon HD 8850M has 640 Shader Processing Units and the NVS 2100M has 16. However, the actual shader performance of the Radeon HD 8850M is 496 and the actual shader performance of the NVS 2100M is 9. The Radeon HD 8850M having 487 better shader performance and an altogether better performance when taking into account other relevant data means that the Radeon HD 8850M delivers a significantly smoother and more efficient experience when processing graphical data than the NVS 2100M.

The Radeon HD 8850M transistor size technology is 12 nm (nanometers) smaller than the NVS 2100M. This means that the Radeon HD 8850M is expected to run slightly cooler and achieve higher clock frequencies than the NVS 2100M.

The Radeon HD 8850M requires 45 Watts to run and the NVS 2100M requires 14 Watts. The Radeon HD 8850M requires 31 Watts more than the NVS 2100M to run. The difference is significant enough that the Radeon HD 8850M may have a slight adverse affect on your yearly electricity bills in comparison to the NVS 2100M.