In terms of overall gaming performance, the graphical capabilities of the AMD Radeon HD 4290 are significantly better than the Nvidia Quadro FX 2000 .

The Radeon HD 4290 was released over three years more recently than the FX 2000, and so the Radeon HD 4290 is likely to have far better driver support, meaning it will be much more optimized and ultimately superior to the FX 2000 when running the latest games.

Both GPUs exhibit very poor performance, so rather than upgrading from one to the other you should consider looking at more powerful GPUs. Neither of these will be able to run the latest games in any playable way.

The Quadro FX 2000 and the Radeon HD 4290 have the same amount of video memory, but are likely to provide slightly different experiences when displaying game textures at high resolutions.

The FX 2000 has 12.8 GB/sec greater memory bandwidth than the Radeon HD 4290, which means that the memory performance of the FX 2000 is slightly better than the Radeon HD 4290.

The Quadro FX 2000 has 4 Shader Processing Units and the Radeon HD 4290 has 40. However, the actual shader performance of the FX 2000 is 2 and the actual shader performance of the Radeon HD 4290 is 18. The Radeon HD 4290 having 16 better shader performance is not particularly notable, as altogether the FX 2000 performs better when taking into account other relevant data.